Within-Subjects Design In a within-subjects design, subjects give responses across multiple conditions or across time. In other words, measures are repeated across levels of some condition or across time points. For example, subjects can report how happy they feel when they see a sequence of positive pictures and another sequence of negative pictures. In this case, we’d observe each subjects’ happiness in both positive and negative conditions. As another example, we could measure subjects’ job satisifcation every month for 3 months.